Effects of drug abuse, addiction and health


By Dr Azadeh

7 million people suffer from illicit drug disorder and one in four deaths can be attributed to alcohol, tobacco, and illicit or, prescription drug use.
Drugs are chemicals that affect the body and brain. Different drugs can have different effects. Some effects of drugs include health consequences that are long-lasting and permanent. They can even continue after a person has stopped taking the substance.
What is drug abuse?
Clinically known as substance use disorder, drug abuse or addiction is caused by the habitual taking of addictive substances. Drugs include alcohol, marijuana, hallucinogens and opioids. Substance use disorder is a disease, causing people to compulsively use drugs despite consequences.



Effects of drug abuse on health
Substance use disorders are associated with a wide range of short- and long-term health effects. They can vary depending on the type of drug, how much and how often it’s taken and the person’s general health. Overall, the effects of drug abuse and dependence can be far-reaching. They can impact almost every organ in the human body.
Side effects of drug addiction may include:
· A weakened immune system, increasing the risk of illness and infection
· Heart conditions ranging from abnormal heart rates to heart attacks and collapsed veins and blood vessel infections from injected drugs
· Nausea and abdominal pain, which can also lead to changes in appetite and weight loss
· Increased strain on the liver, which puts the person at risk of significant liver damage or liver failure
· Seizures, stroke, mental confusion and brain damage
· Lung disease
· Problems with memory, attention and decision-making, which make daily living more difficult
· Global effects of drugs on the body, such as breast development in men and increases in body temperature, which can lead to other health problems
The most severe health consequences of drug abuse are death. Deaths related to synthetic opioids and heroin have seen the sharpest rise. In the past 12 months, 212,000 people aged 12 or older have used heroin for the first time. Every day, more than 90 Americans die after overdosing on opioids.

There are a few ways a person can take drugs, including injection, inhalation and ingestion. The effects of the drug on the body can depend on how the drug is delivered. For example, the injection of drugs directly into the bloodstream has an immediate impact, while ingestion has a delayed effect. But all misused drugs affect the brain.
They cause large amounts of dopamine, a neurotransmitter that helps regulate our emotions, motivation and feelings of pleasure, to flood the brain and produce a “high.” Eventually, drugs can change how the brain works and interfere with a person’s ability to make choices, leading to intense cravings and compulsive drug use. Over time, this behavior can turn into a substance dependency, or drug addiction.
Today, more than 7 million people suffer from an illicit drug disorder, and one in four deaths results from illicit drug use. In fact, more deaths, illnesses and disabilities are associated with drug abuse than any other preventable health condition.
People suffering from drug and alcohol addiction also have a higher risk of unintentional injuries, accidents and domestic violence incidents.
The good news is: Substance use disorders are treatable.


Effects of drug abuse on unborn babies
Illicit drug use poses risks for pregnant women and their babies. Drugs may contain impurities that can be harmful to an unborn baby. Pregnant women who use drugs may be more likely to harm the fetus with risky behaviors and poor nutrition.
Drug use can lead to premature birth or low birth weight. It can also cause the baby to have withdrawal symptoms (sometimes in the form of neonatal abstinence syndrome), birth defects or learning and behavioral problems later in life.

How can addiction harm other people?
Beyond the harmful consequences for the person with the addiction, drug abuse can cause serious health problems for others. Three of the more devastating and troubling consequences of addiction are:
· Negative effects of prenatal drug exposure on infants and children.
A mother’s abuse of heroin or prescription diploids during pregnancy can cause a withdrawal syndrome (called neonatal abstinence syndrome, or NAS) in her infant. It is also likely that some drug-exposed children will need educational support in the classroom to help them overcome what may be subtle deficits in developmental areas such as behaviour, attention, and thinking. On-going research is investigating whether the effects of prenatal drug exposure on the brain and behaviour extend into adolescence to cause developmental problems during that time period.


Effects of drug addiction on the brain
All drugs–nicotine, cocaine, marijuana and others–affect the brain’s “reward” circuit, which is part of the limbic system. This area of the brain affects instinct and mood.
Drugs target this system, which causes large amounts of dopamine—a brain chemical that helps regulate emotions and feelings of pleasure—to flood the brain.
This flood of dopamine is what causes a “high.” It’s one of the main causes of drug addiction.

Although initial drug use may be voluntary, drugs can alter brain chemistry. This can actually change how the brain performs and interfere with a person’s ability to make choices.
It can lead to intense cravings and compulsive drug use. Over time, this behavior can turn into a substance dependency or drug and alcohol addiction.
Alcohol can have short- and long-term brain and disrupts the brain’s communication pathways. These can influence mood, behavior and other cognitive function.

Brain damage may also occur through alcohol-induced nutrition deficiencies, alcohol-induced seizures and liver disease. In pregnant women, alcohol exposure can impact the brains of unborn babies, resulting in fetal alcohol spectrum disorders.
It is reported that alcohol-induced brain problems can often be corrected with proper treatment. Abstinence from alcohol for months or years can help partially repair thinking abilities, like memory skills.

Drug effects on behavior
Substance use disorders can lead to multiple behavioral problems, both in the short- and long-term, which can include:
These effects of drug abuse have serious consequences, like missed work, punishable offenses, accidents and injuries. In fact, alcohol and drugs are partly to blame in an estimated 80 percent of offenses leading to jail.
These incidents include domestic violence, driving while intoxicated and offenses related to damaged property. Legal and illegal drugs excluding alcohol are involved in about 16 percent of motor vehicle crashes. In the past year, almost 12 million people drove under the influence of illicit drugs, and almost injured drivers tested positive for drug involvement.

The use of alcohol with medicines or illegal drugs may increase the effects of each.
Alcohol abuse patterns vary. Some people drink and may be intoxicated (drunk) every day. Other people drink large amounts of alcohol at specific times, such as on the weekend. It is common for someone with an alcohol or drug problem to call in sick for work on Monday or Friday. He or she may complain of having a virus or the flu. Others may be sober for long periods and then go on a drinking binge that lasts for weeks or months.

Someone with alcohol dependence may suffer serious withdrawal symptoms, such as trembling, delusions, hallucinations, and sweating, if he or she stops drinking suddenly (“cold turkey”). After alcohol dependence develops, it becomes very hard to stop drinking without outside help. Medical detoxification may be needed.
Substance abuse refers to the harmful or hazardous use of psychoactive substances, including alcohol and illicit drugs. Psychoactive substance use can lead to dependence syndrome – a cluster of behavioural, cognitive, and physiological phenomena that develop after repeated substance use and that typically include a strong desire to take the drug, difficulties in controlling its use, persisting in its use despite harmful consequences, a higher priority given to drug use than to other activities and obligations, increased tolerance, and sometimes a physical withdrawal state.

Policies which influence the levels and patterns of substance use and related harm can significantly reduce the public health problems attributable to substance use, and interventions at the health care system level can work towards the restoration of health in affected individuals.
3 tips that can help:
An addiction therapist can be a valuable resource. Instead of directly challenging the behavior, they seek to guide the individual to see the truth for themselves.
An addict will usually be more willing to talk with someone who has been there and understands what it’s like. This is why Alcoholics Anonymous is such a powerful resource.
Even if an addict is in a place where they don’t want help, recovery resources such as books, audio and video can still change the trajectory and get them closer to moving in the direction of recovery.
Every journey to recovery looks different. But, one thing they all have in common is hope! Below are links to three real addiction stories of individuals in the process of overcoming their addiction.
For further information check with Anti-drug agencies, email toazadehhassanmd1[email protected], Text only 002207774469 .working days between 3-6pm.

Author DR AZADEH Senior Lecturer at the University of the Gambia, Senior Consultant Physician. Clinical Director Medicare Clinic.